全文获取类型
收费全文 | 5352篇 |
免费 | 477篇 |
国内免费 | 378篇 |
出版年
2023年 | 63篇 |
2022年 | 92篇 |
2021年 | 139篇 |
2020年 | 144篇 |
2019年 | 185篇 |
2018年 | 212篇 |
2017年 | 189篇 |
2016年 | 212篇 |
2015年 | 226篇 |
2014年 | 359篇 |
2013年 | 379篇 |
2012年 | 211篇 |
2011年 | 256篇 |
2010年 | 194篇 |
2009年 | 314篇 |
2008年 | 345篇 |
2007年 | 283篇 |
2006年 | 257篇 |
2005年 | 237篇 |
2004年 | 209篇 |
2003年 | 200篇 |
2002年 | 162篇 |
2001年 | 113篇 |
2000年 | 106篇 |
1999年 | 102篇 |
1998年 | 96篇 |
1997年 | 65篇 |
1996年 | 70篇 |
1995年 | 69篇 |
1994年 | 79篇 |
1993年 | 54篇 |
1992年 | 63篇 |
1991年 | 41篇 |
1990年 | 48篇 |
1989年 | 49篇 |
1988年 | 36篇 |
1987年 | 46篇 |
1986年 | 21篇 |
1985年 | 43篇 |
1984年 | 43篇 |
1983年 | 30篇 |
1982年 | 38篇 |
1981年 | 32篇 |
1980年 | 22篇 |
1979年 | 19篇 |
1978年 | 14篇 |
1977年 | 4篇 |
1976年 | 7篇 |
1975年 | 7篇 |
1973年 | 6篇 |
排序方式: 共有6207条查询结果,搜索用时 15 毫秒
51.
Proton-enhanced carbon-13 magnetic resonance measurements have been made of the natural abundance carbon-13 carbons in hydrated Lα phase dispersions of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) codispersed with cholesterol or with the polypeptide gramicidin A′. The carbonyl group spectrum consists of a superposition of two peaks derived from the two carbonyl sites within the lipid. In the Lα phase of DMPC both carbonyl sites contribute axially symmetric spectra, one with a chemical shift anisotropy of –29 ppm and the other with a chemical shift anisotropy of less than –5 ppm. The chemical shift anisotropy of the broader carbonyl resonance was found to increase with increasing cholesterol content. However, in DMPC dispersions with gramicidin A′, the chemical shift anisotropy of the broader carbonyl signal initially increased slightly from that of pure DMPC and then decreased with increasing concentrations of gramicidin A′. The width of the narrower spectral component was essentially unaltered by cholesterol or gramicidin A′. The presence of a narrow component at all concentrations of cholesterol or gramicidin A′ suggests that it is unlikely that any significant conformational changes have occurred at the carbonyl level of the bilayer. We propose that the major effect of cholesterol or gramicidin A′ is to alter the molecular order parameter, Smol, which reflects the range of angles through which the local molecular long axis of the phospholipid is tumbling. 相似文献
52.
M Yoshida 《Biochemical and biophysical research communications》1983,116(1):217-221
In order to examine a possibility that the high acidic amino acid region in the nonhistone protein HMG(1+2) is concerned with the Mg2+-, or Ca2+-dependent unwinding of DNA by the HMG(1+2) (1,2), poly-L-glutamic acid was employed as an acidic model peptide for thermal melting temperature analysis. The poly-L-glutamic acid bound to DNA either in the presence or absence of Mg2+. The poly-L-glutamic acid unwound DNA double-helix to a similar extent to HMG(1+2) in the presence of Mg2+ or Ca2+, but not in the absence of them. These results may suggest that the high acidic amino acid region in HMG(1+2) participates in Mg2+-, Ca2+-dependent unwinding of DNA double-helix. 相似文献
53.
Larvae of the cockroach Diploptera punctata were reared in isolation, in pairs, or in groups of 8–10. Duration of larval development, age at each ecdysis, weights at birth and ecdyses, and adult head-capsule width were measured. Duration of larval development was longer and adult size was larger in isolated animals than in animals reared in pairs and groups. The effect of isolation on development was more pronounced in males. All females had 4 larval instars, whereas males had 3 or 4 instars. The proportion of males with 4 larval instars was higher among animals reared in isolation. There was no difference in the duration of larval development or adult size between pair- and group-reared animals. The sex of animals in the group did not affect adult size or the duration of larval development. Males which underwent 3 or 4 larval instars had different schedules of moulting. Rates of growth of males of both instar types reared in isolation and pairs were similar. Greater adult weight of isolated animals and 4-instar-type males was a result of their longer duration of larval development. Both a higher rate of growth and longer duration of larval development contribute to the larger adult size of females than males. 相似文献
54.
Carol S. Surowy Nathan A. Berger 《Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression》1983,740(1):8-18
Acceptor proteins for poly(adenosine diphosphoribosyl)ation were determined in resting human lymphocytes, in lymphocytes with N-methyl-N′-nitro-N-nitrosoguanidine-induced DNA damage and in lymphocytes stimulated to proliferate by phytohemagglutinin. Kinetic studies showed that the increase in ADP-ribosylation which occurred in response to N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) treatment was greater in magnitude but more transient in duration than that which occurred in phytohemagglutinin-stimulated cells. Gel electrophoretic analyses revealed that MNNG treatment and phytohemagglutinin stimulation both caused an increase in ADP-ribosylation of poly(ADP-ribose) polymerase and core histones. In MNNG-treated cells, an increase in ADP-ribosylation of histone H1 was also observed. In contrast, phytohemagglutinin-stimulated cells showed no increase in ADP-ribosylation of histone H1. In MNNG-treated cells there was also ADP-ribosylation of a protein of molecular weight 62 000, while in phytohemagglutinin-stimulated cells there was a marked increase in ADP-ribosylation of a protein of molecular weight 96000. MNNG treatment of phytohemagglutinin-stimulated cells produced a pattern of ADP-ribosylation that appeared to be due to the combined effects of the individual treatments. 3-Aminobenzamide effectively inhibited ADP-ribosylation under all treatment conditions. 相似文献
55.
Gregory B. Pollock 《Journal of evolutionary biology》1989,2(3):205-221
Critique of Wynne-Edwards' views on population regulation and sociality suppose a population of discrete, mutually exclusive groups essential to his thought. Yet both his past and present work focus on continually distributed, philopatric populations; his critics have argued the untenability of a position never his own. Wynne-Edwardsian ‘group selection’ focuses on local population productivity under philopatry. A ‘group’ is a local confluence of genotypes which need not be reified, and group selection consists of the differential replication (hence heritability) of the local social environment in which a genotype is embedded. Differential productivity contingent on social environment can eliminate some relational structures on genotypes in favor of others, creating an expanding wave of population productivity as in Wright's shifting balance metaphor. Such a process is inherent in the evolution of reciprocity, where cooperators must cluster to successfully invade a population of defectors. Regulation of resource exploitation in continuously distributed populations may be modeled as overlapping n-person Prisoner's Dilemmas, where each individual participates in several distinct commons and defection represents local over-exploitation of resources. 相似文献
56.
Robert W. Mitchell 《Zoo biology》1989,8(2):125-137
The functions and social consequences of infant-adult male interaction in a captive group of lowland gorillas were evaluated. The two males repeatedly attempted to interact with the infant, the infant sometimes attempted to interact with the males, and the mother usually interrupted interactions between male and infant. Infant-directed actions by the two males frequently showed their interest in the infant and infrequently showed care giving toward her; their other infant-directed actions occurred near the time of excitement or of playful actions between adults. Male-directed actions by the infant frequently showed its interest in one male and infrequently showed care seeking from him. All infant-adult male interactions but one occurred in the less stimulating of the gorillas' two enclosures. Boredom and the mother's frequent thwarting of contact between a male and infant are suggested as influences on the males' interest in the infant. The data suggest that availability of interesting objects alleviated the boredom of captivity for males and thus dissuaded them from seeking stimulation which sometimes resulted in harmful behaviors toward the infant. 相似文献
57.
Thomas F. Hourigan Frank G. Stanton Philip J. Motta Christopher D. Kelley Bruce Carlson 《Environmental Biology of Fishes》1989,24(2):105-116
Synopsis The foraging behavior and associated morphology of the feeding apparatus of three sympatric species of angelfishes, Holacanthus tricolor, Pomacanthus arcuatus and Pomacanthus paru were studied at St. Croix, U.S. Virgin Islands. All three had overlapping diets, consisting of algae and numerous species of sponges. The two Pomacanthus species also fed on gorgonians. The morphology of the dentition, jaws and gill rakers was similar in all three species. Male Holacanthus tricolor defended territories overlapping the foraging areas of two to four females. Within the male's territory, females defended smaller territories against other females of the same size, but tolerated smaller females. In contrast, both Pomacanthus spp. formed pairs which defended intraspecific feeding territories. 相似文献
58.
H. Preuschoft 《Human Evolution》1989,4(2-3):145-156
The variation of body shape among prosimians is reviewed. Special emphasis is placed on the selective advantages, that is
the mechanical reasons, to which variants of the locomotor apparatus can be traced back.
There are differences found in the cheiridia, but at present they cannot be explained in terms of mechanics; there is nearly
no knowledge about the mechanical meaning of their diversity. Myological characteristics of taxa can be explained mechanically,
but this has not yet been done.
Well known are variations of body proportions. These discriminate higher taxa, and are largely coincident with the often-used
locomotor categories. In spite of this, there are only few sound arguments about the real biomechanic value of characteristic
proportions for a given locomotor mode. What is known on this field, is reviewed. Progress can be made only, if the mechanical
conditions, set by postural behavior and locomotion, are understood completely.
The subtle distinctions between lower taxonomic units can normally be identified only on the basis of detailed and quantified
analyses of movements on one hand, and of biometrics on the other. In the few cases in which such studies have been made,
the differences of morphology fit to the mechanical requirements of locomotion which also differ only in quantitative details. 相似文献
59.
S. Laurie Sanderson 《Oecologia》1990,84(2):272-279
Summary The term specialized has been used to describe species that possess unique functional attributes and/or a narrow, stereotyped range of attributes, but there are few comparative functional analyses of specialists and generalists. If species with functional morphological specializations are capable of functioning over a broad range, the link between morphology and ecology may be relaxed under certain environmental conditions. In this study, high-speed films of jaw movements during prey capture were compared statistically for three coexisting coral reef fish species in the family Labridae, one trophic specialist and two trophic generalists. The trophic specialist possessed a unique functional feature related to the movement of the hyoid in the floor of the mouth, while the trophic generalists were not observed to possess any functional specializations. All three species showed functional versatility in that they were able to adjust their prey capture mechanism in response to the evasive potential of the prey. The functional versatility of trophic specialists has implications for ecomorphological studies, since species characterized as possessing unique functional or morphological features may demonstrate marked flexibility in ecological variables such as diet or foraging behavior, decreasing the likelihood of identifying correlations between morphology and ecology. 相似文献
60.
Interspecific relations of African crocidurine shrews (Mammalia: Soricidae) based on multivariate analysis of mandibular data 总被引:1,自引:0,他引:1
P. M. BUTLER R. S. THORPE F.L.S. M. GREENWOOD 《Zoological Journal of the Linnean Society》1989,96(4):373-412
Eighteen graded non-metric characters and 30 measurements of the mandible and lower dentition were used to investigate the grouping of African species of the genera Crocidura, Suncus and Sylvisorex. Seventy-seven taxa (species, subspecies and synonyms), including four European species, were represented by one to nine mandibles (147 mandibles in all), and the means of four Pleistocene African species were also included. The metric data were subjected to principal component and canonical variate analyses, and the non-metric data to principal component analysis. Grouping was detected by comparing the results of the three analyses. Six groups are recognized within the genus Crocidura , typified by C. fumosa, C. turba, C. russula, C. fuscomurina, C. hirta and C. flavescens. Sylvisorex is divisible into two groups, typified by S. lunaris and S. granti. The African species of Suncus (but not the introduced species, S. murinus ) form a single group, which is linked to the Sylvisorex granti group. Suncus is closely related to, or convergent with, the Crocidura fuscomurina group. The first non-metric principal component, the second metric principal component and the second canonical variate are significantly correlated. It is considered that these together represent a general trend of evolutionary advance. Phylogenetic relations are discussed in the light of this; Crocidura may be diphylefic. 相似文献